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Prepregnancy GLP-1RA use improves maternal lipid metabolism via liver-secreted FGF21 during pregnancy in HFD-fed dams

And, as we do not yet understand the mechanism behind semaglutide's impact on cardiovascular disease, researchers have called for caution when it comes to widespread prescription of this medication for purposes beyond weight loss and diabetes management

After four weeks, the dose increases to 0.5 mg weekly, and if needed, can be increased further up to a maximum of 2.4 mg weekly

Many patients find that sipping fluids between meals rather than with meals reduces bloating and discomfort

Some have a fear of needles

Any UK prescriber considering its use must be aware that it would be supplied as an imported unlicensed medicine on a named-patient basis, with full prescriber responsibility